Ractopamine hydrochloride

Ractopamine is a drug that is used as a feed additive to promote leanness in pigs raised for their meat. The feed additive Paylean, produced by the U.S. company Elanco Animal Health, contains ractopamine hydrochloride. Paylean was approved by the United States Food and Drug Administration on December 22, 1999, and has also been approved in more than 20 countries, including Australia, Brazil, Canada, Mexico, and Thailand. However it is banned in other countries, including China; which prohibited its use in 2002.

Ractopamine in feed for animals is responsible for dramatic muscle growth, yet it is not a steroid or hormone, but rather a compound known as a beta agonist. Only a trace amount of ractopamine need be added for a marked increase in protein and decrease in fat accretion in animals, in particular swine. For the last 90 pounds of live weight gain, a mere 18.5 grams of ractopamine added to a ton of feed (20 ppm) will increase protein by 24% and decrease fat by 34%.